Milla Jovovich is not only married to the franchise Resident Evil but also to the the director of the Resident Evil series, Paul W.S. Anderson.
Meaning also she knows what is happening behind the scenes. One thing she told is that the fifth installment will most probably be called Resident Evil: Retribution though Milla tweets that, “I have to ask Paul 2 b sure.”
Anderson is incredibly focused on making his new movie look a lot like the video games on which this franchise is based. Anderson spends his time watching game footage for inspiration. Jovovich also explains, Paul has kids that are professional players. All they do is play the games until they master every level and unlock every code. They play the games for weeks and give Paul the footage.
The fifth Resident Evil is currently slated for a September 14, 2012 release date with Milla Jovovich, as always, returning to kick as iconic Alice.